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As mentioned in previous sections, folate is required for the synthesis of SAM, the primary methyl donor in cellular methylation reactions

used the microfluidic trypsin treatment method to analyze the effect of TMZ on single-cell adhesion of U87 GBM cells, proposing that the ability to regulate cell adhesion was also a significant aspect in drug evaluation ( Figure 4 (i) GBM-on-a-chip including side channels for nutrients and drugs to be delivered to cells and stroma compartments for culture of GBM cells

This includes nausea, vomiting, constipation, abdominal pain, and diarrhea

We examined the effect of primary human CAFs on p53 induction and cell viability in prostate cancer cells on treatment with chemotherapeutic drugs