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this is reversible on discontinuing the drug

10.1016/j.cub.2018.05.094 137 SongY.WangB.ZhuX.HuJ.SunJ.XuanJ.et al (2021)

Keywords: high cholesterol diet, LDL cholesterol, virgin olive oil, oxidative stress, rats

223 Under hypoxic pressure, autophagy orchestrates selective degradation of cellular components, including mitochondria (mitophagy), ER (ER-phagy), lipid droplets (lipophagy), ribosomes (ribophagy), nuclei (nucleophagy), and peroxisomes (pexophagy), 224,225,226,227 thereby sustaining tumor metabolism and viability