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As COPD progresses, the lungs struggle to absorb and deliver enough oxygen, and symptoms can worsen

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Incorporation of genetic variants identified through genome wide association and CVD cohort studies has successfully refined CVD risk prediction models indicating that heritable genetic variants play an integral role in CVD pathogenesis and progression

[Article] [PubMed] [PMC]24

In conclusion, our data highlight that the choice of first-line biological therapies is highly impacting the outcome of UC and cannot be fully compensated by later treatments