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However, excessive type 2 immunity may lead to the development of allergic diseases and pathological fibrosis (36, 37)

Indeed, Mao and colleagues (283) found that global KO mice, in contrast to conditional -cell ZnT8 KO mice, exhibited adipocyte hypertrophy due to lipid accumulation in all major white adipose depots (VAT and SAT), accumulation of lipids in the liver, and increased expression of genes related to fatty acid synthesis and uptake

If you choose to drink, consider different transport options - public transport, rideshare or organising a friend to be a designated driver

Additionally, advocating for policies that support the development and reimbursement of novel therapies can improve patient access (159)