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By employing physical encapsulation or chemical conjugation, these platforms circumvent the physicochemical limitations inherent to many PROTACs, thereby liberating medicinal chemistry efforts from the empirical correction of poor drug-like properties and enabling a sharper focus on optimizing the ternary complex for maximal degradation activity [56, 276,277,278]

However, stronger muscles support joints reducing injury risk and improving rehabilitation outcomes

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The microbiota has been extensively studied for its role in modulating immune responses to cancer and maintaining gut homeostasis, leading to investigations into its potential to modify the outcomes of radiotherapy [15, 16]