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While NNMT influences energy metabolism in both adipose tissue and liver, its expression suppresses NAD + levels specifically in adipose tissue

In experimental literature, it is sometimes mentioned as part of what researchers informally call the wolverine stack due to its observed tissue-repair activity in preclinical models

For instance, the release of Smac/Diablo into the cytosol ensures the efficiency of caspase 3 in proteolyzing target proteins through inhibition of inhibitor of apoptosis proteins (IAPs)