Naunyn Schmiedebergs Arch Pharmacol 382:331345 Genovese G, Khler AK, Handsaker RE, Lindberg J, Rose SA, Bakhoum SF, Chambert K, Mick E, Neale BM, Fromer M, Purcell SM, Svantesson O, Landn M, Hglund M, Lehmann S, Gabriel SB, Moran JL, Lander ES, Sullivan PF, Sklar P, Grnberg H, Hultman CM, McCarroll SA (2014) Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence
These creams target conditions such as melasma, post-inflammatory hyperpigmentation (PIH), sunspots, and general dullness
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Abbreviations 2-DG: 2-deoxy-D-glucose -KG: -ketoglutarate ART: Aspect ratio ASCL1: Achaete-scute homologue 1 CCLE: Cancer Cell Line Encyclopedia COX4I1: Cytochrome C Oxidase Subunit 4 Isoform 1 COX5B: Cytochrome C Oxidase Subunit 5B CPT1: Carnitine palmitoyltransferase 1 DAPI: 4,6-diamidino-2-phenylindole ECAR: Extracellular consumption rate EF: Elongation factor EMT: Epithelial-to-mesenchymal transition GDH: Glutamate dehydrogenase GLS: Glutaminase GSEA: Gene set enrichment analysis GSH: Glutathione GSSG: Glutathione disulfide HAD: 3 hydroxyacyl coenzyme A dehydrogenase HGB: Hemoglobin ICI: Immune checkpoint inhibitor IDH: Isocitrate dehydrogenase IHC: Immunohistochemistry LDH: Lactate dehydrogenase MPC: Mitochondrial pyruvate carrier NADH: Nicotinamide adenine dinucleotide ND1: NADH dehydrogenase 1 NDUFA5: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 5 NE: Neuroendocrine NES: Normalized enrichment score NEUROD1: Neurogenic differentiation factor 1 OCR: Oxygen consumption rate OXPHOS: Oxidative phosphorylation PBS: Phosphate-buffered saline POU2F3: POU class 2 homeobox 3 SCLC: Small cell lung cancer SCLC-AN: ASCL1/ NEUROD1 expressing SCLC SDH: Succinate dehydrogenase TCA: Tricarboxylic acid cycle TRX: Thioredoxin T2DM: Type II diabetes mellitus YAP1: Yes-associated protein 1 References Megyesfalvi Z, Gay CM, Popper H, Pirker R, Ostoros G, Heeke S et al
