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Some people may experience dark under-eye circles due to factors like poor sleep, stress, or nutritional deficiencies

If this beneficial effect and resolving adequately the anatomical imbalance in venous drainage would not occur, centrally, a harmful inability to drain venous blood adequately for a given cerebral blood inflow without raising venous pressures, suddenly goes to such venous and intracranial hypertension [60,61,62,63,64], as seen in the controls with the permanently occluded superior sagittal sinus

Treatment of PDNP Effective management of PDPN primarily relies on pharmacological interventions, supplemented by non-pharmacological therapies tailored to individual patient needs