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Selenium deficiency also causes diarrhea by disrupting intestinal flora, and through intestinal flora causes pathological changes such as intestinal inflammation, autophagy, endoplasmic reticulum stress, apoptosis, tight junctions, and abnormal smooth muscle contraction [36]

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosomepositive leukemia

These findings are consistent with previous reports showing that traditional herbal formulations can attenuate mucosal inflammation and restore epithelial integrity in UC models [46, 47]