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dissolve platinating agents that are not soluble in water (Fig

Additionally, SF demonstrated protective effects in rodent models of vascular cognitive impairment induced by ischemia at 56.4 mol/kg twice a week (112), subarachnoid hemorrhage at 282 mol/kg every 24 h (113), and intracerebral hemorrhage at 5.64 mol/kg twice a day (114), with upregulation of Nrf2 and reduced inflammation reported in the latter two

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281,282,283 In the TME, Gln metabolic reprogramming is essential for the survival of tumor cells and immune cells, and there is competition for Gln uptake