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doi:10.1007/978-1-4614-8948-1_1

Optional research biomarkers: senescence markers (p16^INK4a, SA--gal), SASP cytokine profile (IL-6, IL-1, MMPs) if lab resources permit

Administered at doses of 5002000 mg/kg/day for 20 days, the treatment provided strong evidence of its neuroprotective efficacy (Sohn et al., 2021)

Epigenetic programming of mitochondrial homeostasis The epigenetic landscape, as described above, provides a stable yet malleable layer of control that can program the mitochondrial capacity of cardiomyocytes