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10.3889/oamjms.2016.040 Open Access Maced J Med Sci

In the early stages of ferroptosis, tumor cells release damage-associated molecular patterns (DAMPs), such as high-mobility group box 1 (HMGB1) and ATP

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The gut microorganism can enter the underlying tissue compartment due to the breakdown of intestinal epithelial tight junction, and further accelerating the intestinal barrier damage (Hu et al., 2022)