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In the case of chronic myeloid leukemia (CML), for example, chromosomal translocation t(9;22)(q34;q11) is the leukemia-driving event, which generates the fusion between BCR and ABL genes, and the resultant Bcr-Abl kinase allows cells to survive and proliferate in a growth factor-independent manner 2,3

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A proteins hydrodynamic volume is a key structural feature that changes significantly when the globular protein denatures and unfolds (Tanford, 1968

These miRNAs can enhance translation within mitochondria, in contrast to the repressive action of cytoplasmic miRNAs [37]