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The results of Lei et al

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Materials and methods Study design This multicenter retrospective cohort study including patients with confirmed COVID-19 infection was conducted during the first wave of the COVID-19 outbreak, between March and May 2020, when Italy was in strict lockdown

By contrast, the stress sensor GADD45 was detected within only early differentiating IRS cells (supplementary figure 3c), while the ROS-protective protein heme oxygenase-1 (HO-1) was intensely expressed in a small subset of IRS cells located usually in the upper follicle, at the level of the sebaceous gland, where IRS cornification is advanced to complete (supplementary figures 3g and 3h)