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These three B vitamins are not merely general health boosters

Cell culture studies demonstrate stimulation of beta-3 adrenergic receptors in adipocytes, enhancing fat oxidation while inhibiting lipogenesis via acetyl CoA carboxylase blockade

The liver stores are a bit irrelevant to someone who has PA or a B12 absorption problem though because the mechanism that is used to release them relies on the same mechanism that is used to absorb most dietary B12 so accessing any stores is at best very inefficient

Indeed, recent work with transgenic mice suggests that folate deficiency may predispose heterozygotes for the CBS defect to basal hyperhomocysteinemia (Lentz et al, 2000)