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El mayor porcentaje de casos de hiperpigmentacin, corresponde a lesiones de origen melnico que incluyen formas benignas y malignas, razn por la cual, se debe distinguir del melanoma, definido como un tipo de cncer de piel producido por la proliferacin de melanocitos atpicos ( 5 , 9 , 13 )

[DOI] [PubMed] [Google Scholar] 4.Ishikawa I, Aoki A, Takasaki A

Used solely for in vitro experiments and cannot be: Used in clinical trials involving humans Administered to humans as part of an experiment or investigation Supplied to another party for human investigational use Description of Melatonan 2 A synthetically produced peptide Melatonan 2, a variant of Melatonan 1, mimics non-selectively the action of melanocortin peptides by binding their receptors, which are involved in various functions in human body as pigmentation, immune response or even in sexual functions

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