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ROS: Reactive Oxygen Species

Ferritin in blood plasma can store up to 4500 atoms of iron per protein molecule, which is a well-known catalyst of lipid peroxidationa chain reaction, which produces a slew of free radicals, leading to DNA, protein and cell membrane damage

Over the past 34 years, during 28 market corrections, active strategies (as represented by the Morningstar Large Blend Category) outperformed passive strategies (S&P 500 Index) 21 times, with an average outperformance of 109 basis points

This systemic effect is unique to injectable administration and explains why many researchers prefer this route