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Identification of hub miRNAs in NOA The degree of module connection can be determined by calculating the absolute value of Pearsons correlation

The mechanism is that sesamin up regulated CREB gene by activating cAMP/PKA signaling pathway, then up regulated the expression of tyrosinase and MITF, and finally induced melanin synthesis (Jiang et al., 2011)

Mechanism of Interest Its structure allows investigation of peptide-driven intracellular cascades and metabolic regulatory pathways in experimental environments

For tumor passaging to new mice, each fresh tumor samples from PGXG1 were divided into pieces of 0.5*0.5*0.5 cm and remove necrotic tissue