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Similarly, neonates of mothers treated with phenobarbital, a drug known to stimulate hepatic UGT activity and the concentration of ligandin, and neonates of heroin users have less than the anticipated severity of physiologic jaundice

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The triggered signaling process leads to the expression of proinflammatory cytokine-inducing transcription factors, such as NF-kB, as well as to activate interferon regulatory factors that mediate the type I interferon-dependent antiviral response [17]

PMID 24847166