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CONFLICT OF INTEREST The authors declare there is no conflict of interest in the authorship or publication of this manuscript

This ferroptosis-induced pancreatic cancer development could be linked to macrophage infiltration and polarization, mediated by the release of 8-OHG (8-hydroxy-2-deoxyguanosine) resulting from ferroptotic damage and subsequent activation of the STING1-dependent DNA sensor pathway [209, 210]