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Common causes of B12 deficiency can include: Limited dietary intake (common in strict vegan or vegetarian diets) Pernicious anemia, an autoimmune condition that prevents proper B12 absorption in the stomach Gastrointestinal surgeries that remove part of the stomach or small intestine Age-related declines in stomach acid production Long-term use of certain medications, such as metformin or proton pump inhibitors, which can reduce the bodys ability to properly absorb vitamin B12

TB-500 (synthetic TB4) has been clinically tested for its wound healing potential, with the following two studies worth noting: In a randomized, double-blind, placebo-controlled study with dose escalation, patients suffering from venous stasis ulcers were administered synthetic TB4 locally over a period of 84 days

The combination shows particular effectiveness for chronic injuries that have failed to heal properly, overuse injuries in athletes, and post-surgical recovery

Distinct Differences in Sites of Metastatic Disease May Contribute to Poorer Outcomes Observed in Patients with BRAF Mutant Colorectal Cancers, 2010