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In particular, evidence from a large number of preclinical studies suggests that API has promising effects in the prevention and treatment of a variety of liver diseases, including multifactorial liver injury, non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, liver fibrosis and liver cancer

7A), and both the high and low BPA groups exhibited a trend of decreased cyp19a1b expression

These results suggested that RcGPX4 played a negative role in freezing tolerance by suppressing the genes expression of the ICE1-CBF-COR cascade 3 and ABA signaling pathways (Figure 9)