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This article explores the evidence, contributing factors, and practical guidance

Persistent nausea may prevent adequate food and fluid intake, while vomiting and diarrhea can lead to dehydration and electrolyte imbalances

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In addition, the concentration of cyanocobalamin is detectable in plasma only in smokers due to the increased cyanide exposure of cigarette smoke in combination with the dietary supplement (Domke et al., 2004)