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The clinical application of alpha-lipoic acid in metabolic dysfunction-associated steatotic liver disease Metabolic Dysfunction-associated Steatotic Liver Disease is a chronic liver disease characterized by excessive fat accumulation in the liver, insulin resistance, oxidative stress and inflammatory responses, which can progress to non-alcoholic steatohepatitis, fibrosis, cirrhosis and even hepatocellular carcinoma

Yet, despite the constant ebb and flow of meals, snacks, and fasts, the amount of glucose in our blood remains remarkably steady

Therefore, individuals who consume alcohol heavily should ensure adequate thiamine supplementation before and during ALA therapy

Cao et al., 2013)