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Results: We find that both preconditioning the host with AAV8-Tbg-P21 and the HGF+EGF mRNA-LNP treatments significantly augment transplanted PHH survival and proliferation in vivo, evidenced by histological quantification of transplanted cells and human serum albumin levels in comparison to control

By phagocytosing chemically modified low-density lipoprotein (LDL), these cells become foam cells, which make up the largest part of the core of the plaque