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Chin Chem Lett 34:107727

C., Lambert, K

Glucose and amino acids cannot diffuse passively into the brain because of their polarity, so they are usually transported by carrier-mediated transcytosis

Furthermore, oxidative stress has been extensively studied in cells expressing mutant SOD1 as well as in transgenic SOD1 G93A mice, revealing that various SOD1 mutants increase oxidative stress and dysregulate redox homeostasis (Ferri et al., 2006