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Macrophage membrane-coated nanocarriers co-modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimers disease mice

Fatty acid oxidation In diet-induced obese mice and ob/ob mice, 50 mg/kg twice daily for 28 days increased whole-body energy expenditure and fatty acid oxidation, reduced fat mass, lowered cholesterol and triglycerides, and improved insulin sensitivity without changing food intake