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Due to their similar structures, both hCG and LH bind to the same LHCGR receptor on Leydig cells, but hCG does so with greater affinity, preferentially inducing cAMP and increasing intracellular Ca, upregulating genes that code steroidogenic enzymes

Because MOTS-C works at the cellular level, many people experience improved stamina, more stable daily energy, and better overall metabolic balance

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The study showing copper peptides increased collagen in 70% of users versus 40% for retinoic acid suggests copper peptides may actually be more effective for collagen building specifically, though retinoids offer additional benefits (texture improvement, dark spot reduction) that copper peptides don't provide as strongly