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For instance, in pancreatic ductal adenocarcinoma (PDAC) cells, inhibiting GSH synthesis alone fails to effectively induce ferroptosis

Dual role of autophagy in hallmarks of cancer

In recent decades, large-scale clinical trans-omics studies allowed the identification of some crucial ferroptosis-related genes as reliable biomarkers to describe the tumor immune microenvironment landscape and predict response to antitumor therapy (Liu S