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Inhibition of histone deacetylase reinstates hippocampus-dependent long-term synaptic plasticity and associative memory in sleep-deprived mice

Higher levels of pro-inflammatory cytokines and glial cell markers were observed, and stool samples had higher concentrations of inflammatory mediators such as TNF-, IL-1, IL-6, and IFN- in PD patients colon biopsy tissues, which indicate gastrointestinal inflammation (84) (Figure 2)

Early administration of the antidote, N-acetylcysteine (NAC), is the most effective treatment to prevent and treat liver injury

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