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Archives of Pharmacal Research, 46 (910), 744770

25 , R78R80 (2015)

The majority of NTHi iron requirement is fulfilled by acquisition of haem therefore compounds that restrict haem-assimilation may have higher therapeutic value than those solely targeting iron acquisition

Although harvests from both 34C and 37C infections contained a similar proportion of empty and full particles, cell culture conditions that are more permissive to viral replication resulted in the production of empty capsids with increased GSH binding (Scheme 1) were sufficiently removed in the GSH FT and did not require further optimization of GSH chromatography parameters for additional clearance