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Kennett GA, Chaouloff F, Marcou M, Curzon G (1986) Female rats are more vulnerable than males in an animal model of depression: the possible role of serotonin

10.1016/j.ebiom.2023.104527 47

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So, after solubilizing glutathione youll want to remeasure the pH of the solution, and add concentrated base to change the pH back to your desired value