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Whether mitochondria directly drive ferroptosis is still controversial, but there is no doubt that it is the main source of reactive oxygen (ROS) in mammalian cells (Murphy, 2009)

Nitro blue tetrazolium is yellow in colour but is changed to blue formazan after phagocytosis

A common area of previous investigation includes the crosstalk between the endoplasmic reticulum (ER) and mitochondria in the kidney

With a standard reduction potential (E0) of 0.44 V, the Fe0 core can reductively dehalogenate chlorinated organic solvents and reduce mobile, high-oxidation-state metals and metalloids to less toxic, immobile forms.51,52 A key example is the reduction of hexavalent chromium:2CrO42 + 3Fe0 + 16H+ 2Cr3+ + 3Fe2+ + 8H2OThe study by Zhang et al.,49 which integrated nZVI with biochar, highlights a common strategy to mitigate the rapid aggregation and surface passivation that plagues bare nZVI