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Pathological Mechanisms and Potential Therapeutic Targets of Pulmonary Arterial Hypertension: A Review Signaling pathways and targeted therapy for pulmonary hypertension Signal Transduction and Targeted Therapy Metabolic reprogramming, oxidative stress, and pulmonary hypertension ScienceDirect The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity ScienceDirect
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