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Epithalons primary mechanism is the induction of telomerase activity in human somatic cells

Studies examining long-term L-citrulline use have demonstrated that supplementation may reduce systolic blood pressure and can reduce diastolic blood pressure at doses greater than or equal to six grams per day.8 Acute use of similar doses has also resulted in positive effects.9 For those at risk of heart disease and hypertension, supplementing citrulline may help prevent the need for medications down the line, though this is a sensitive enough area of your health that you should definitely speak with your doctor before taking it

A subsequent follow-up of this same cohort was conducted, which extended the follow-up period an additional 8 years from that reported in Hall et al

10.1186/s10020-024-00873-0 294 LuL.LiW.SunC.KangS.LiJ.LuoX.et al