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Notably, there are emerging strategies for staging cachexia

Duman et al., 2007

Similarly to IGF-I, vascular endothelial growth factor (VEGF) affects the survival and proliferation of endothelial cells, neurons and astrocytes in the brain, suggesting a potential therapeutic application in PD [32]

Or you could be misdiagnosed with a major depressive disorder or even psychosis and take unneeded psychiatric medications for months (or years) before someone notices you look yellowish and youre finally diagnosed with megaloblastic anemia