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Sahini et al 1996) and as the axial iron coordination sites of heme are unoccupied, it is conceivable that GSH coordinates iron at one of these sites

Despite limited knowledge of the pathogenic contribution of Mtb-induced host DNA methylation changes, in Mtb-infected macrophages, hypermethylation was predominantly observed on genes related to host immune responses, such as NLRP3 inflammasome activation and pro-inflammatory cytokine production