n acetyl l cysteine vs glutathione The Yack on NAC (N-Acetyl-Cysteine) and Parkinson's – Journey with Parkinson's Superior Properties of N-Acetylcysteine Ethyl

2020 Academic Press:1338 46

With age, GSH levels decrease by up to 50% compared to young subjects, contributing to increased oxidative stress and chronic low-grade inflammation (inflammaging). In the anti-ageing field, GSH IV acts on three main levels: direct neutralisation of free radicals and protection of dermal collagen, modulation of inflammation through NF-B inhibition, and reduction of melanogenesis through tyrosinase inhibition with clinically observable effects on skin tone and luminosity. The most robust clinical evidence concerns neuroprotection (improvement of motor symptoms in Parkinson's disease) and protection from chemotherapy-induced neuropathy

Yodh, Theresa M

doi: 10.1134/S1819712421020057 37