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Three weeks later, intraperitoneal injection of clozapine-N-oxide (CNO, a ligand of the chemogenetic designer receptor) at 1 h after morphine administration, which significantly increased both the output and water content of feces in hM3Dq-expressing mice compared to mCherry-expressing control mice (Fig

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Moreover, DFO has been shown to inhibit ferroptosis in SCI (Yao et al., 2019), but whether it directly protects neurons from ferroptosis is unclear