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In a cross-sectional study, mitochondrial fragmentation was specifically observed in the proximal tubules of kidneys from DKD patients

This is probably because (1) PtGa itself is thermodynamically stable ( H f = 55.6 kJ mol 1 ) 18,19 and (2) the atomic radius 26 of Pb (1.80 ) is much larger than those of Pt (1.35 ) and Ga (1.30 ): the diffusion of Pb into the bulk of PtGa is likely to be unfavorable even at 600 C