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EaglesDABoydSJKotakAAllanF.Calorie restriction of a high-carbohydrate diet elevates the threshold of Ptz-induced seizures to values equal to those seen with a ketogenic diet

By inhibiting the PI3K/Akt pathway, GPS can amplify its apoptotic effects, as activated Akt typically promotes cell survival by phosphorylating and inactivating pro-apoptotic proteins

The peptide amplified the anxiolytic action of the benzodiazepine, suggesting potential as an adjunctive therapy that could allow lower doses of conventional anxiolytics