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Another species used for the study of brain metastasis is Drosophila melanogaster

They can be constructed by using a wide range of substrates including organic (e.g., liposomes, micelles, hydrogels, etc.), 17,18,19 inorganic (e.g., metal/metal oxide particles, silica nanoparticles, quantum dots, etc.), 20,21 and biomass-derived materials (e.g., exosomes, cells, bacteria, etc.)

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This process was primarily driven by the abnormal proliferation of Fusobacteriota and Bacteroidota: Bacteroidota could efficiently degrade host mucins and polysaccharides, providing essential carbon and energy sources for the community, while Fusobacteriota might exploit their secreted virulence factors, such as leukotoxins and extracellular proteases, to disrupt the mucosal structure 117