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doi:10.1016/j.bbrc.2014.01.056

These results indicated that methionine-SAM axis is required for mitochondrial OXPHOS, and is responsible for the generation of mitochondrial ROS (mtROS)

10.1074/jbc.M209372200 136 YangW

Researchers have discovered that patients who took isotretinoin also tend to have elevated levels of a certain enzyme called creatine phosphokinase (or CPK)