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Identification of the resulting nontargeted metabolite LC-MS peaks was conducted by: i) matching measured retention times and masses to mixtures of reference metabolites analyzed in each batch

*Correspondence: Armida Mucci, [email protected] These authors share last authorship This article was submitted to Neuropharmacology, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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