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Key Points Aberrant c-MET pathway activation occurs frequently in gastrointestinal tumours and can result from multiple mechanisms, including c-MET protein overexpression, MET amplification or enhanced transcription and/or aberrant autocrine or paracrine secretion of HGF Activated c-MET signalling results in enhanced cancer cell proliferation, survival and invasion

The top ten precursors were then selected for MS2/MS3 analysis

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In healthy adults, plasma concentrations of urolithin A-glucuronide reach a peak of approximately 110 ng/mL and 30 ng/mL at 24 h post consumption of pomegranate juice (107 mg of ellagitannins and ellagic acid) (28) and frozen red raspberry beverage (29 mg of ellagitannins and ellagic acid) (29), respectively