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(ix) Recalculates expenditures used in Shared Savings Program benchmark calculations under this section, and as applicable under 425.654 through 425.662, to exclude the same HCPCS or CPT codes identified as displaying significant, anomalous, and highly suspect billing patterns in calculation of performance year expenditures, in accordance with 425.672

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Experimental studies indicate that calycosin may modulate the Toll-like receptor (TLR) 4/NF-B signaling pathway, suppress the expression of TSLP and IL-33, and increase tight junction proteins such as ZO-1 and occludin in both human immortalized keratinocyte cell line (HaCaT) and mouse AD models (Tao et al., 2017)