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Future research should focus on in-depth analysis of mechanisms and accelerated clinical translation, promoting silybin from the laboratory to the clinic, thus providing more effective and safe treatment options for patients with inflammatory diseases

doi: 10.1016/0006-2952(70)90338-2 227 WongJ

This can include B12, but it can also exclude it depending on the specific supplement, so it's essential to look at the Supplement Facts label of any given B-Complex to know which B Vitamins are included

Moving further, most developing countries do replace their traditional diets, which were once enriched with grains and fibers, with ones that are increasingly high in sweeteners, fats, meats, and dairy products