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High homocysteine levels are associated with reduced fertility in many ways including, poor oocyte quality, miscarriage, hypertension, and low birth weight

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However, the link between the antibiotic and non-antibiotic group is less strong and cross-reactivity is unlikely to arise, but some still advocate avoiding dapsone or sulphasalazine in patients allergic to sulphonamide antibiotics Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor

Instead, each parent has a single non-working SLC22A5 gene for CTD