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Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats

On the other hand, protective and therapeutic groups treated with GbE or LC showed a significant increase in DA, NE, and 5-HT levels and a significant decrease in AchE activity versus PTZ-treated animals in both the tested brain regions

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As is well-known, l-carnitine can adjust many events, such as metabolism of glucose and fatty acids, and has the potential to protect these cellular events in several manners including decreasing the production of reactive oxygen species at different points and maintaining mitochondrial functions (24)