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10.3389/fnut.2023.1243390 161

However, following administration of the ferroptosis inhibitors liproxstatin-1 or ferrostatin-1, the levels of inflammatory factors and ROS are reduced, endogenous antioxidant pathways related to Nrf2, HO-1, and NQO1 are upregulated, transforming growth factor- expression is downregulated, and iron ptosis is reduced in lung tissue [107]